How Lipid Nanoparticles and Spike Drive Multi-Organ Injury

Day 4 · 5:19:00 · Dr. Peter McCullough

• 🧪 Pseudouridylated mRNA in LNPs spreads widely, crosses brain and eye barriers, and drives high full-length spike production and autoimmunity.
• 🗺️ Batch variation, genetics, and imperfect neutralizing antibodies explain why some are spared and others get clots, myocarditis, blindness, or aneurysms.
• 🔬 He ties diverse syndromes to biodistribution of genetic material and spike, calling the design the worst biological idea he has heard—and largely unquestioned in Canadian academia.

Mechanistic map from LNP mRNA to the spectrum of injuries heard at the inquiry.

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Transcript

Dr. Peter McCullough · 5:19:02

Many stopped after one or two shots. In the United States, our estimate now is less than 9% of people are taking boosters. The public knows these vaccines to not, not to be safe. A Rasmussen survey indicated 56% of Americans believe large numbers of deaths have occurred after the vaccine. This is a population-based representative survey. What's gone on? What is going on in the bodies of these vaccine-injured paper, the patients Messenger RNA, which has been pseudourigenated— that means it's been made indestructible by a Nobel Prize-winning process replacing uracil, one of the four base pairs, with pseudouridine. This is injected, it circulates widely in the human body in lipid nanoparticles. Lipid nanoparticles cross the blood-brain barrier, they cross into the eye, they explain all these syndromes that we've heard today. The messenger RNA is readily taken up in the body and the spike protein is produced in large quantities. This lethal protein, it causes cell disruption and death.

Dr. Peter McCullough · 5:20:06

It's expressed on the cell surface as shown at the top. It has homology with over 3 dozen human proteins, so it immediately excites autoimmunity. The body knows the spike protein is not supposed to be here, and so the body tries to envelop the spike protein in phospholipid packets called exosomes. But clearly the spike protein and the amount of spike protein exposed to the body when the vaccine is manyfold greater than the infection. The infection— the, the, the ACE receptor actually catabolizes part of the spike protein. So we get the tip of the spike protein with the infection, but we still get it in our body. The vaccinated get full-length spike protein it trimerizes, and then it travels in the bloodstream. And each person's different depending on where the blood flow happened to go, where the spike protein interacts. That's the reason why we see these array of syndromes. Now, those who took AstraZeneca or Janssen, by the way, made by the same biosecurity firm outside Baltimore, Emergent BioSolutions, that was an adenoviral vector.

Dr. Peter McCullough · 5:21:14

It downloaded the, the genetic code, the DNA code for spike protein It was transcribed, and there's a huge blast of spike protein here, but hopefully the adenoviral vector is gone, and now it's just a matter of getting rid of the residual spike protein. In the, in the United States, about 9% took one of these vaccines. The array of vaccine injury syndromes that you've seen over the course of the last 3 days is mind-boggling of how a single biopharmaceutical product can cause this much disease and damage across so many organ systems. How can that be? Some of you must be wondering, how in the world can one person have blindness, another person have aneurysm, another person have his son die of a cardiac arrest? How can that be from one or two shots? It's because they're genetic. And it's because the protein is gain-of-function research.

Dr. Peter McCullough · 5:22:16

It was designed to kill. In fact, people who have taken these vaccines in many ways are lucky to be alive because their library of antibodies directed against the spike protein must be perfectly neutralizing it. That's the only explanation that exists right now. Now there's variation in the vaccine lots. Some lots probably had very little messenger RNA in it. Some were hyperloaded. There's a website called howbadismybatch.com that one can sort this out, and it's in the peer-reviewed literature, and one is able to evaluate what their risk is with their batch. Each person has their own genetics, and it's been my clinical experience after examining thousands of patients That if anyone has any little flaw in their genetics, in their epigenetics, or in their baseline condition, the vaccine seems to strike at that flaw.

Dr. Peter McCullough · 5:23:20

For example, if someone has a proclivity to blood clotting, they take the vaccine, boom, we, we've seen the biggest blood clots we've ever seen in medical history. A blood clot in the leg before the pandemic was about an inch long. I have patients where the entire leg is a solid blood clot, even extending up to the inferior vena cava. We are seeing anyone who has a polymorphism, a genetic difference in their contractile proteins in the heart, the sarcomere, the other cysteine proteins, the non-sarcomeric proteins, to be the ones who are hit with myocarditis. For an example. So it's a multifactorial, uh, Venn diagram of who's going to end up with a vaccine injury and who's going to be spared. When I went on the Joe Rogan podcast towards the end of 2021, that was the toughest question I asked by Joe Rogan. He said, Dr. McCullough, if these vaccines are so bad, why isn't everybody injured and dead?

Dr. Peter McCullough · 5:24:23

I didn't have an answer, but I have an answer It's partly the variation in the concentration in the vials, which Public Health Canada and the Canadian agencies have refused to examine the concentration of messenger RNA or adenoviral DNA in the vials or examine for contaminants. It's individual baseline variation, and then it's the library of antibodies that they raise against the spike protein. If their immune system is perfect They can neutralize every single bit of that spike protein, hopefully forever, and they never have a problem. But in an important paper by Yonkers from Harvard with little boys who are suffering myocarditis in Mass General Hospital and a control group of boys who were fine from taking the vaccine, the boys who had myocarditis, the antibodies were missing the spike protein. They were just off, and the spike protein was allowed to cause damage. So there's a great diversity of these vaccine injuries.

Dr. Peter McCullough · 5:25:23

To make it more complicated, the spike protein shown on the left, it folds, it goes in different patterns, and it has different kind of characteristics of its own in the human body. So the spike protein in one human body is not the same in another human body. It may fold in a way where it damages neurologic receptors in the spinal cord, causing transverse myelitis. It may fold in a way where it attaches to red blood cells and forms micro blood clots and forms, uh, blindness in the eye. And you can see on the right here, it goes everywhere from the biodistribution. And what we understand is this messenger RNA or adenoviral DNA in lipid nanoparticles and spike protein go everywhere in the human body. This is the last thing you would want with a genetic code that is coding for a lethal protein.